Cleanroom & Critical Environments

The Role of Negative Pressure Rooms in Modern Healthcare

PAC Designs a Crucial Cleanroom Facility for the Webb Space Telescope

USP Postpones USP 797 and USP 795 Deadline Until Further Notice (Nov 2019)

As of November 22nd, 2019, the USP will delay implementing previously suggested changes to USP 795 and 797 chapters until further notice.

Medical Device Cleanroom Construction Part 6: Pressure Differentials, Humidity and Temperature Calibration

The central controller integrates the data from both the thermostats, fan filter processors, and room-side environmental sensors. Fan filter speed is then adjust by each group to achieve the specified room pressure while at ideal temperature and humidity.

Medical Device Cleanroom Construction Part 5: HVAC Balancing & Calibration

Before cleanroom validation, a cleanroom requires mechanical calibration. HVAC calibration first ensures that the room meets the performance parameters which would deliver the expected results during final ISO validation, such as differential pressure, air change rates, and uniform airflow distribution.

Medical Device Cleanroom Construction Part 4 – VCT Flooring Design

There are a few final preparations required before the final cleanroom flooring installation. Here’s what to expect and consider for cleanroom tile installations and flooring installation.

Cleanroom Fan Filter Testing and Maintenance – HEPA Filter Replacement and Troubleshooting

How do I know when to replace my cleanroom HEPA air filters? How do I test a cleanroom HEPA filter? What are the best practices for cleanroom HEPA filter replacement?

What Are the Differences Between Corona and Alpha Ionization?

This post covers the different types of static control ionization equipment and technologies. Which is best for your application?

Medical Device Cleanroom Construction Part 3: Fan Filter Units – Ceiling Grids

In this post, we overview technical considerations for clean room fan filter unit selection, installation, and features. You’ll learn how PAC approaches design and configuration

Medical Device Cleanroom Construction Part 2: Doors, Electrical, and Layout

In medical device cleanrooms, a common configuration is an ISO 8 gowning room and ISO 7 primary production area. A cascading air flow design and

Medical Device Cleanroom Construction Part 1: Walls and Installation

How is a medical device cleanroom built? Here’s a component-by-component guide to ISO Class 7 cleanroom construction.

E-Liquid Clean Rooms – E-Liquid Labs and Cleanroom Classifications

What are the advantages of cleanrooms for e-liquids? What are the American E-liquid standards for the FDA, and ISO cleanrooms? Does the FDA require a cleanroom for e-liquids and e vape products?

USP 800 Cleanroom Construction Hazardous Compounding: Options and Alternatives

There are a few options available to cleanroom facilities who require new upgrades for USP 800 compliance. The best option will depend on the variables

Polycellulose & Polyester Cleanroom Wipe Supplies

Here’s the guide to buying cleanroom wipes that stay on-budget. Differing package sizes, bulk counts, edge types, material options, cloth size, weights, ISO class, substrates, ionic levels…comparing cleanroom wipes is mind numbing. 50% of leading cleanroom wipe advertisers don’t even offer prices online!